Research field
Oncology Research
Oncology research deciphers the molecular origins of cancer, develops new therapeutic strategies, and seeks to prevent cancer recurrence. Pan-cancer genomic atlases have catalogued the driver mutations, mutational signatures, and chromosomal rearrangements across all major cancer types, enabling precision oncology drug matching. Immune checkpoint inhibitors blocking PD-1/PD-L1 and CTLA-4 have transformed outcomes in melanoma, lung cancer, and bladder cancer. Liquid biopsy captures circulating tumor DNA from blood for minimal residual disease monitoring and early detection. FLASH radiotherapy delivers therapeutic doses in milliseconds, sparing normal tissue by exploiting oxygen depletion kinetics. CAR-T cell therapies are expanding from blood cancers into solid tumor targets through next-generation antigen targeting and engineering strategies.
Top institutions
MD Anderson Cancer Center
Memorial Sloan Kettering
Francis Crick Institute
Institute Gustave Roussy
Princess Margaret Cancer Centre
Subfields
Key technologies
Single-Cell Multi-Omics
Immune Checkpoint Inhibitors
ctDNA Sequencing
CAR-T Engineering
FLASH Radiotherapy
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