Researcher

Sarah Teichmann

Profile

Sarah Teichmann is a pioneering computational and experimental biologist at the Wellcome Sanger Institute, where she co-founded and leads the Human Cell Atlas (HCA) — a landmark international consortium mapping every cell type in the human body using single-cell RNA sequencing (scRNA-seq). Her laboratory has developed foundational methods for single-cell transcriptomics, spatial transcriptomics, and multi-omics profiling that are now standard tools in biomedical research worldwide. Teichmann's group was among the first to systematically characterize the immune microenvironment of human tumors at single-cell resolution, revealing previously unknown immune cell subpopulations that have become targets for cancer immunotherapy. Her work on T cell differentiation and thymic development has reshaped understanding of adaptive immunity. As a heavy consumer and developer of single-cell sequencing platforms, microfluidics equipment, FACS sorters, and bioinformatics pipelines, her lab represents a major institutional buyer of genomics instrumentation. She has published over 300 peer-reviewed papers, holds multiple patents on single-cell methods, and collaborates extensively with companies including 10x Genomics and Illumina. Teichmann was elected Fellow of the Royal Society in 2020 and has received numerous awards including the EMBO Gold Medal.

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